RSV Vaccine Market Trends, Sales, Supply, Demand and Analysis by...

RSV Vaccine Market Trends, Sales, Supply, Demand and Analysis by Forecast to 2035

Posted 2025-09-08 11:04:04

The RSV vaccines landscape has transformed significantly since the approval of three RSV vaccines, namely Arexvy, Abrysvo and mRESVIA, since 2023. Ever since then, with the application of more advanced platforms to develop innovative vaccines, the life expectancy of patients with RSV diseases has risen remarkably.

The majority (46%) of the developers were established during the period post-2010. Moreover, there has been an increase in the number of developers entering the RSV vaccine domain over the past decades, reflecting a stable and enticing industry for the new entrants. Examples of developers established post-2020 include (in reverse chronological order, established post-2019) RNApeak (2021), RVAC Medicines (2021), Starna Therapeutics (2021), Vaxmed (2020), Vernagen (2021) and RNAImmune (2020).

It is worth highlighting that around 70 RSV vaccines are under different stages of development for patients suffering with respiratory syncytial virus infections. In fact, over 60% of the RSV vaccines are currently being evaluated in clinical trials to assess the safety and efficacy of these vaccines against RSV diseases.

Over 35% of the RSV vaccines are a type of live attenuated vaccines, owing to the fact that live attenuated vaccines contain a live pathogen and the immune system reacts very well to these vaccines, resulting in a robust and long-lasting immune response. Further, close to 30% of the vaccines are subunit / viral-like-particle vaccines, which only contain inactive fragments of the pathogen and not the whole organism, thus reducing the chances of cross infections. Notable examples of live attenuated vaccines include (in alphabetical order, intramuscular vaccines) ChAdV155-RSV (GlaxoSmithKline), KD-409 (KM Biologics), RSV MEDI ΔM2-2 (National Institute of Allergy and Infectious Diseases) and SP0125 (Sanofi).

Patent analysis: protecting intellectual property generated within RSV vaccines market- The majority (22.4%) of the patents were published in 2022, followed by patents published in 2024 (22.1%). This decrease in the number of patents published in 2023 is indicative of the growing preference for alternative RSV treatments such as monoclonal antibodies. In addition to this, majority (51%) of the patents were filed in North America, followed by Europe (16%). This is an indicative of robust patent activity for RSV vaccines in North America, owing to the recent approvals of several RSV vaccines in the respective region. However, the continuous expansion of RSV vaccine market is anticipated to drive patent filings as companies strive to differentiate their product portfolio to meet healthcare needs.

Clinical trial analysis – evaluating the overall potential of RSV vaccines market- Most of the clinical trials assessing the safety and efficacy of these RSV vaccines in human beings, are in phase I (38%). This can be attributed to the fact that the application of RSV vaccines has shown a significant prevention of RSV and related complications among vulnerable patient groups. Owing to which, an upsurge has been witnessed in the R&D activity in this domain, and a large number of novel vaccine candidates have been identified that are being currently evaluated in the early phases of clinical trials. Additionally, it is worth highlighting that 31% of the clinical trials evaluating RSV vaccines are phase III studies, indicating that in the coming years more targeted drugs are likely to enter the RSV vaccine market.

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